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1

Valvular Heart Disease

There is a great deal of attention on cardiovascular disease and the health of critical arteries, but I seldom read preventative approaches to slowing valvular disease. Could you please comment on what individuals living at younger ages (40 and younger) can do to delay intervention?

3

Blood-Based Test for  Colorectal Cancer Screening

Peter, In The New England Journal of Medicine, March 14, 2024, vol. 390 no. 11, Guardant Health has a blood test for colorectal cancer. - should this test be added to annual blood testing for years that a colonoscopy is not performed for people over 50 yo? "In an average-risk screening population, this cfDNA blood-based test had 83% sensitivity for colorectal cancer, 90% specificity for advanced neoplasia, and 13% sensitivity for advanced precancerous lesions. (Funded by Guardant Health; ECLIPSE ClinicalTrials.gov number, NCT04136002.)"

3

Ed Thorp and longevity

Did you read the recent interview with Ed Thorp in Bloomberg referencing your book? Any chance we can get him on The Drive podcast?

1

Negative study for time restricted eating?

https://www.acpjournals.org/doi/10.7326/M23-3132?utm_source=cmpnr&utm_campaign=lfa_240419_1&utm_content=1&cmp=1&utm_medium=email

1

Covid vaccine negatively affects all cause mortality lifespan?

Peter, love you. Love your podcast. Here's a study that is talking about all cause mortality numbers in relation to the covid vaccine. https://open.substack.com/pub/wherearethenumbers/p/italian-study-calculates-covid-19?r=z0dcz&utm_medium=ios Appreciate your thoughts as always!